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Being a central nerve system depressant that works as a sedative and hypnotic for the treatment of sleeping disorders (sleeping condition), and as a narcotic and muscle relaxant. Methaqualone, or brand name Quaalude, is a central nervous system depressant that acts as a sedative and hypnotic.

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To begin, In prescribe doses, Quaaludes promotes relaxation, sleepiness and sometimes a feeling of euphoria.However, It causes a drop in blood pressure and slows the pulse rate.So, these properties are the reason why it is initially thought to be a useful sedative and anxiolytic. Quaaludes are not recommended during pregnancy as the effects on human fetal development are not clear.

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When it was a legal medicine, methaqualone was available in tablet and capsule form and came in different strengths. Oral Quaalude (Methaqualone) dosages was 75-150mg for light sedation. A common prescribed dose was 300mg. Up to 600mg was used for strong sedation. Tolerance develops rapidly and some users may take up to 2000mg daily to achieve the same effects. Onset of action is approximately 30 minutes after taking Quaalude (Methaqualone) and duration of action is between 5 to 8 hours.

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By 1965, it was the most commonly prescribed sedative in Britain, where it has been sold legally under the names Malsed, Malsedin, and Renoval. In 1965, a methaqualone/antihistamine combination was sold as the sedative drug Mandrax, by Roussel Laboratories (now part of Sanofi-Aventis). In 1972, it was the sixth-bestselling sedative in the US, where it was legal under the brand name Quaalude. Quaalude in the United States was originally manufactured in 1965 by the Fort Washington, Pennsylvania, based pharmaceutical firm William H. Quaaludes for sale here

Methaqualone is a common recreational and self-medication drug in South Africa and other of the former Frontline States, including Mozambique, Angola, Zambia and Zimbabwe. This medication is still being produced under the aegis of the apartheid-era South African government’s Project Coast directed by Dr Wouter Basson in powder and tablets form. The methaqualone and MDMA, along with cocaine and other empathogens and aphrodisiacs as well as muscle relaxants and incapacitating anticholinergic deliriants were considered for non-lethal riot-control use.

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